Mechanisms of Drug Resistance in Relapse and Refractory Multiple Myeloma
نویسندگان
چکیده
منابع مشابه
Mechanisms of Drug Resistance in Relapse and Refractory Multiple Myeloma
Multiple myeloma (MM) is a hematological malignancy that remains incurable because most patients eventually relapse or become refractory to current treatments. Although the treatments have improved, the major problem in MM is resistance to therapy. Clonal evolution of MM cells and bone marrow microenvironment changes contribute to drug resistance. Some mechanisms affect both MM cells and microe...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2015
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2015/341430